International Guidelines for Sepsis and Septic Shock
Posted in Lectures on 21 November 2017
John E. Mazuski
Professor of Surgery
Washington University, St. Louis, USA
Dr. Mazuski, on behalf of the Surgical Infection Society of North America, presents , in this talk the International Guidelines for Sepsis and Septic Shock, given during the 30th Annual European Congress on Surgical Infections, held in Hamburg (Germany) last June. Firstly, the definitions of sepsis and septic shock are reviewed, updating their prior definitions. Then recommendations for early-goal directed therapy are reviewed, including the modifications of clinical and laboratory criteria. Prospective randomized trials (ProCESS, ARISE, ProMISe, PRISM) are discussed, comparing the mortality results for Early-Goal Directed Therapy vs standard therapy. Finally, some aspects of the Surviving Sepsis guidelines that are relevant to patients with surgical infections are discussed.